Is atorvastatin 40 mg a high-intensity?
Therefore, the 2013 American College of Cardiology/American Heart Association (ACC/AHA) guideline on treatment of blood cholesterol recommends high‐intensity statins, including atorvastatin 40 or 80 mg and rosuvastatin 20 or 40 mg, for patients with atherosclerotic cardiovascular disease.
Which statins are high-intensity?
— High-intensity statin therapies are atorvastatin (40–80 mg) or rosuvastatin (Crestor; 20–40 mg). Moderate-intensity statin therapies include atorvastatin (10–20 mg), rosuvastatin (5–10 mg), simvastatin (20–40 mg), pravastatin (40–80 mg), and several others.
Is atorvastatin a moderate-intensity statin?
Statin Use for the Prevention of Cardiovascular Disease in Adults: A Systematic Review for the U.S. Preventive Services Task Force [Internet]….Table 1Statin Dosing and ACC/AHA Classification of Intensity.
| Statin | Atorvastatin | |
|---|---|---|
| Dosage | Low-intensity (LDL-C reduction <30%) | NA |
| Moderate-intensity (LDL-C reduction 30% to <50%) | 10 to 20 mg | |
| High-intensity (LDL-C reduction >50%) | 40 to 80 mg |
Who qualifies for high-intensity statin?
Four groups of patients are recommended for intense statin treatment: Adults with clinical ASCVD, which encompasses coronary artery disease, peripheral artery disease, transient ischemic attack or stroke. Adults age 40 to 75 with diabetes. Adults of any age with LDL above 190.
Is 40 mg of atorvastatin too much?
Conclusions: Atorvastatin in daily dose of 40 mg is a safe and well tolerable medication for the treatment for dyslipidemic disorders in patients of different clinic profile and cardiovascular risk groups in common medical practice.
What does atorvastatin 40 mg do?
Atorvastatin is used along with a proper diet to help lower “bad” cholesterol and fats (such as LDL, triglycerides) and raise “good” cholesterol (HDL) in the blood. It belongs to a group of drugs known as “statins.” It works by reducing the amount of cholesterol made by the liver.
Is 80mg of statin high?
What is already known? High dose statins (40mg and 80 mg atorvastatin) are important in reducing ASCVD events. However, these high statin doses are associated with increased adverse effects like liver enzyme elevation, new onset diabetes mellitus and myalgia/myopathy which are related to dose.
What is so bad about statins?
Very rarely, statins can cause life-threatening muscle damage called rhabdomyolysis (rab-doe-my-OL-ih-sis). Rhabdomyolysis can cause severe muscle pain, liver damage, kidney failure and death. The risk of very serious side effects is extremely low, and calculated in a few cases per million people taking statins.
What is the strongest statin?
Rosuvastatin and atorvastatin are the strongest statins because they have long half-lives. – Atorvastatin, simvastatin, and lovastatin are metabolized by the P450 cytochrome 3A4, which is inhibited by many other drugs and may thereby increase the risk of myopathy.
Can you take a statin every other day?
Background: Statins are generally well tolerated, but some patients discontinue therapy secondary to adverse effects. Dosing a statin (rosuvastatin) every other day (EOD) may provide significant lipoprotein changes while avoiding common adverse effects in this statin-intolerant population.
Is pitavastatin high intensity?
In contrast, “high-intensity or high-dose statins” in Japan, such as pravastatin 40-80 mg, atorvastatin 10-20 mg, rosuvastatin 5-10 mg, and pitavastatin 2-4 mg are listed within the “moderate-intensity” statin group in the ACC/AHA guideline [5].
What happens if you take 2 atorvastatin by mistake?
Taking an extra dose of atorvastatin by accident is unlikely to harm you. Talk to your pharmacist or doctor if you’re worried or take more than 1 extra dose.
Who should not take atorvastatin calcium?
Atorvastatin is used in adults and children who are at least 10 years old. You should not take atorvastatin if you are pregnant or breast-feeding, or if you have liver disease. Stop taking this medication and tell your doctor right away if you become pregnant.
What does atorvastatin look like?
What Atorvastatin Tablets looks like and contents of the pack. Atorvastatin 10, 20 and 40 mg film-coated tablets are white with a round shape, embossed “10”, “20” and “40”, respectively, on one side. Atorvastatin Tablets are available in blister packs containing 28 film-coated tablets.
What does atorvastatin treat?
Atorvastatin is used to treat high cholesterol, and to lower the risk of stroke, heart attack, or other heart complications in people with type 2 diabetes, coronary heart disease, or other risk factors.
What is atorvastatin calcium?
Atorvastatin calcium is an organic calcium salt composed of calcium cations and atorvastatin anions in a 1:2 ratio. It contains an atorvastatin (1-).