Which adverse effect is associated with Filgrastim?
Filgrastim injection products may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: redness, swelling, bruising, itching or a lump in the place where the medication was injected. bone, joint, back, arm, leg, mouth, throat, or muscle pain.
Is Filgrastim dangerous?
Filgrastim can cause your spleen to become enlarged and it could rupture (tear). Call your doctor right away if you have sudden or severe pain in your left upper stomach spreading up to your shoulder.
Is Filgrastim a glycoprotein?
G-CSF (Neupogen or Filgrastim), granulocyte-colony stimulating factor, is a glycoprotein that has multiple functions in both physiological and pathophysiological conditions. G-CSF stimulates the BM to produce granulocytes and stem cells and release them into the bloodstream.
How is Filgrastim produced?
Filgrastim is produced by bacteria through the use of genetic engineering and recombinant DNA technology. Filgrastim belongs to a class of drugs called colony-stimulating factors because of their ability to stimulate cells in the bone marrow to multiply and form colonies of new cells.
When should filgrastim not be given?
Filgrastim Precautions: The manufacturer recommends that the first dose of filgrastim be given no sooner than 24 hours after chemotherapy. Your doctor will discontinue therapy with filgrastim when your white blood cell count has reached acceptable levels.
How long does it take for filgrastim to wear off?
Neulasta is a long lasting medicine, with peak levels achieved 24 hours after injection, levels drop considerably over the first 7 days and after 14 days there is only a small amount remaining in the body.
Where do you inject filgrastim?
Choose an injection site from one of the following areas (see Figure 1).
- The outer area of your upper arms.
- Your abdomen (belly), except for the 2-inch area around your belly button.
- The middle of the front of your thighs.
- The upper areas of your buttocks.
Is filgrastim a G-CSF?
FILGRASTIM, G-CSF (fil GRA stim) is a granulocyte colony-stimulating factor that stimulates the growth of neutrophils, a type of white blood cell (WBC) important in the body’s fight against infection.
When should you not give filgrastim?
Where should filgrastim be injected?
Choose an injection site The outer area of your upper arms. Your abdomen (belly), except for the 2-inch area around your belly button. The middle of the front of your thighs. The upper areas of your buttocks.
Can you drink alcohol with filgrastim?
The drinking of alcohol (in small amounts) will not affect the safety or usefulness of filgrastim. is best to use birth control while being treated with filgrastim. Tell your doctor right away if you or your partner becomes pregnant.
When is the best time to inject filgrastim?
Start using the medicine 24 hours or more after you finish your chemotherapy. However, do not use it within 24 hours before you begin another chemotherapy. Allow the medicine to warm to room temperature for 30 minutes before you inject it.
What are the side effects of a filgrastim injection?
Filgrastim, filgrastim-sndz, and tbo-filgrastim may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: redness, swelling, bruising, itching or a lump in the place where the medication was injected. bone, joint, or muscle pain.
How does filgrastim work in the bone marrow?
Filgrastim helps the bone marrow to make new white blood cells. When certain cancer medicines are used to fight cancer cells, they also affect the white blood cells that fight infections. Filgrastim is used to prevent or reduce the risk of infections while you are being treated with cancer medicines.
What are the side effects of general anesthesia?
Complications of General Anesthesia. Most healthy people tolerate general anesthesia without issue. Those who do suffer side-effects or complications typically have mild, transient symptoms that are easily managed. The following are possible complications of general anesthesia: Sore throat. Nausea and vomiting. Damage to teeth.
How is filgrastim used in the treatment of neutropenia?
Filgrastim injection is used to treat neutropenia (low white blood cells) that is caused by cancer medicines. It is a synthetic (man-made) form of a substance that is naturally produced in your body called a colony stimulating factor.