What is the meaning of transposition of great vessels?

Transposition of the great vessels (TGV) is a group of congenital heart defects involving an abnormal spatial arrangement of any of the great vessels: superior and/or inferior venae cavae, pulmonary artery, pulmonary veins, and aorta.

What is the difference between the L transposition defect and the D transposition defect?

L-transposition of the great arteries (L-TGA) is also known as congenitally corrected transposition of the great arteries. This condition is different from D-transposition of the great arteries (d-TGA). In L-TGA, the right and left lower pumping chambers of the heart (ventricles) are switched.

How common is transposition of the great arteries?

Occurrence. The Centers for Disease Control and Prevention (CDC) estimates that about 1,153 babies are born with TGA each year in the United States. This means that every 1 in 3,413 babies born in the US is affected by this defect.

Is transposition of the great arteries fatal?

Transposition of the great arteries or TGA is a potentially fatal congenital heart malformation where the pulmonary artery and the aorta are switched. The switch means that the aorta, which normally carries oxygenated blood, carries deoxygenated blood.

How is TGA diagnosed?

The cardiac ultrasound can usually detect transposition of the great arteries (TGA). If your newborn baby was born with a bluish tint to his skin, or if your child is experiencing certain symptoms, your pediatrician will immediately refer you to a pediatric cardiologist, who will perform a physical exam.

Is TGA heart disease?

Transposition of the great arteries (TGA) is a type of heart defect that your baby is born with (congenital). In this condition, the two arteries that carry blood out of the heart aren’t connected as they should be. They are reversed (transposed).

Can TGA be detected before birth?

TGA is sometimes diagnosed by fetal ultrasound before the baby is born. First trimester screening for chromosomal abnormalities is a good screening tool to identify patients who might be at an increased risk for cardiac defects.

How will TGA be treated?

They include: Medication. The medication prostaglandin E1 (alprostadil) helps keep the connection between the aorta and pulmonary artery open (ductus arteriosus), increasing blood flow and improving mixing of oxygen-poor and oxygen-rich blood until surgery can be performed. Atrial septostomy.

Can TGA cause heart failure?

Transposition of the great arteries (TGA) is a congenital heart defect that is associated with congestive heart failure, tricuspid regurgitation, and arrhythmias.

Can TGA be detected by ultrasound?

In addition to the classical ultrasound signs, other two-dimensional ultrasound markers such as an abnormal right convexity of the aorta, an I-shaped aorta, and the “boomerang sign” may also be used to diagnose TGA in the prenatal period.

When was the transposition of the great vessels described?

Transposition of the Great Vessels was first described in 1797 by Matthew Baillie. Echocardiography of a complex transposition with a ventricular septal defect and pulmonary stenosis. Abbreviations: LV and RV=left and right ventricle, PT=pulmonary trunk, VSD=ventricular septal defect, PS=pulmonary stenosis.

What do you call transposition of the great arteries?

This type of transposition of the great arteries is sometimes also called congenitally corrected transposition. However, the blood usually circulates correctly through the heart and body.

What to do before surgery for transposition of great vessels?

Before surgery: For newborns with transposition, prostaglandins can be given to keep the ductus arteriosus open which allows for the mixing of the otherwise isolated pulmonary and systemic circuits.

Where does deoxygenated blood go in Dextro transposition?

In dextro-Transposition of the great arteries (dextro-TGA) deoxygenated blood from the right heart is pumped immediately through the aorta and circulated to the body and the heart itself, bypassing the lungs altogether, while the left heart pumps oxygenated blood continuously back into the lungs through the pulmonary artery.

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