What is MTTP gene?
The MTTP gene provides instructions for making a protein called microsomal triglyceride transfer protein.
What gene causes Abetalipoproteinemia?
Abetalipoproteinemia is caused by mutations in the MTTP gene and is inherited as an autosomal recessive genetic condition. Genetic diseases are determined by two alleles, one received from the father and one from the mother.
What does microsomal triglyceride transfer protein do?
Microsomal triglyceride transfer protein (MTP) transfers lipids (TGs, cholesteryl esters, and phosphatidylcholine) into apoB-containing lipoproteins such as very-low-density lipoprotein (VLDL) particles originating from the liver. MTP also transfers lipids to chylomicrons originating from the intestine (Fig.
What is the full form of MTTP?
Microsomal triglyceride transfer protein large subunit is a protein that in humans is encoded by the MTTP gene. MTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein.
What is McLeod syndrome?
Collapse Section. McLeod neuroacanthocytosis syndrome is primarily a neurological disorder that occurs almost exclusively in boys and men. This disorder affects movement in many parts of the body. People with McLeod neuroacanthocytosis syndrome also have abnormal star-shaped red blood cells (acanthocytosis).
Are triglycerides proteins?
Triglycerides are simple lipid which constituted one molecule of glycerol and three molecules of fatty acids. Triglyceride is the storage form of lipid , which is used for energy production.