What causes woolly hair?

Mutations in the JUP, DSP, DSC2, and KANK2 genes cause keratoderma with woolly hair types I through IV, respectively. The JUP, DSP, and DSC2 genes provide instructions for making components of specialized cell structures called desmosomes.

What is woolly hair?

Woolly hair is a rare congenital abnormality of the structure of the scalp hair characterized by tightly coiled hair involving part or the entire scalp occurring in an individual of non-negroid origin. [1] It was first observed and described by Gossage in 1907 in a European family.

Is woolly hair dominant or recessive?

Autosomal dominant hereditary woolly hair is more commonly encountered than the autosomal recessive form. The mode of transmission of the latter is still debated [7, 21]. The etiology of diffuse partial woolly hair and of sporadically occurring woolly hair nevus is unknown.

What texture is woolly hair?

People with these conditions have hair that is unusually coarse, dry, fine, and tightly curled. In some cases, the hair is also sparse. The woolly hair texture typically affects only scalp hair and is present from birth.

What causes Uncombable hair syndrome?

Uncombable hair syndrome is caused by mutations in the PADI3, TGM3, or TCHH gene. These genes provide instructions for making proteins that help give structure to the hair strand (shaft). The proteins produced from the PADI3 and TGM3 genes modify the protein produced from the TCHH gene, known as trichohyalin.

What is Trichorrhexis?

Trichorrhexis nodosa is a common hair problem in which thickened or weak points (nodes) along the hair shaft cause your hair to break off easily.

What causes unmanageable hair syndrome?

What does Uncombable Hair Syndrome look like?

Uncombable hair syndrome is a condition that is characterized by dry, frizzy hair that cannot be combed flat. This condition develops in childhood, often between infancy and age 3, but can appear as late as age 12. Affected children have light-colored hair, described as blond or silvery with a glistening sheen.

Is Bad hair genetic?

Frizzy, misbehaving hair may be inherited, according to a new study. Researchers studying mice have found the Frizzled 6 gene to control hair patterns and humans have a gene that’s virtually identical.

How do you treat weak spots in hair?


  1. Gentle brushing with a soft brush instead of aggressive brushing or ratting.
  2. Avoiding harsh chemicals such as those used in straightening compounds and perms.
  3. Not using a very hot hair dryer for long periods and not ironing the hair.
  4. Using a gentle shampoo and a hair conditioner.

What is woolly hair syndrome?

Woolly Hair Syndrome. Woolly Hair Syndrome is a rare congenital abnormality of the structure of the scalp hair marked by extreme kinkiness of the hair.

What is wooly hair?

Wooly hair. Wooly hair (alternatively spelled ” Woolly hair”) is the presence of hair typical of those of sub-Saharan ancestry on people from other ethnic backgrounds, hair which, under the microscope, appears tightly coiled, and presents at birth or infancy usually as a solitary inherited trait in an autosomal dominant fashion.

What is hair gene?

The type and amount of melanin in hair is determined by many genes, although little is known about most of them. The best-studied hair-color gene in humans is called MC1R. This gene provides instructions for making a protein called the melanocortin 1 receptor, which is involved in the pathway that produces melanin.