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What are the steps of an autologous stem cell transplant?

Undergoing an autologous stem cell transplant involves:

  • Taking medications to increase the number of stem cells in your blood.
  • Filtering stem cells from your blood (apheresis).
  • Undergoing high doses of cancer treatment (conditioning).
  • Receiving an infusion of stem cells.

How long are you in hospital for autologous stem cell transplant?

The average time for the chemotherapy, transplant, and recovery is approximately 3 weeks. Not all transplant centers require that patients remain in the hospital after the infusion of stem cells.

What is the success rate of autologous stem cell transplant?

The standard treatment for relapsed and primary refractory HL is salvage chemotherapy followed by high-dose chemotherapy and autologous stem cell transplantation (ASCT), which has shown a 5-year progression-free survival rate of ∼50%–60%.

Do you lose weight during stem cell transplant?

Our study, with 180 patients one of the largest to address incidence and consequences of weight loss during allogeneic SCT, confirms previous findings of a significant decrease of BMI during allogeneic stem cell transplantation [11]: in our cohort the median decrease was 6.6% for all patients, but in fact more than …

Do you need chemo before stem cell transplant?

Before you get your cells on transplant day, you will get chemotherapy (with or without radiation) to prepare your body to receive them. This is called the preparative regimen, or conditioning regimen. The preparative regimen includes chemotherapy (chemo) given to you through your central line.

Can you live a normal life after stem cell transplant?

A stem cell transplant may help you live longer. In some cases, it can even cure blood cancers. About 50,000 transplantations are performed yearly, with the number increasing 10% to 20% each year. More than 20,000 people have now lived five years or longer after having a stem cell transplant.

How much weight do you lose after stem cell transplant?

55.6% of patients experienced a significant weight loss of ≥5% with a median decrease of 9.2% in BMI.

What is the recovery time for a stem cell transplant?

Recovery from a stem cell transplant can be slow. It takes 6 to 12 months to recover normal blood cell levels and immune function. During this time, it’s important for you to take steps to reduce the risk of infection, get plenty of rest, and follow your doctors’ instructions about medicines and checkups.

What is the survival rate of a stem cell transplant?

About 25%–40% of people over the age of 60 are expected to survive 3 years or more. If an allogeneic stem cell transplant is done during first remission, the 5-year disease-free survival rate is 30%–50%.

What to expect after a stem cell transplant?

After the Stem Cell Transplant Your new immune system starts to work. After two to four weeks, the new stem cells graft to your bone marrow and start to make new white blood cells. If you received donor cells, you will get antibiotics and anti-rejection drugs to help your body accept the transplanted cells.

Can you die from stem cell transplant?

People can die from the toxicities of a bone marrow or stem cell transplant. The risk is dependent on factors such as the type of donor, the reason for the transplant as well as other medical problems the recipient has.

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