What are the side effects of linezolid?
What Are Side Effects Associated with Using Linezolid?
- red blood cell deficiency.
- low blood platelet count.
- abdominal pain.
- loose stools.
What drug class is Linezolid?
Linezolid is a synthetic antibiotic belonging to a new class of antimicrobials called the oxazolidinones. Linezolid disrupts bacterial growth by inhibiting the initiation process of protein synthesis—a mechanism of action that is unique to this class of drugs.
Is linezolid hard on the kidneys?
Overall, linezolid elimination is not affected by renal function, and no dosage adjustment is warranted for patients with renal impairment.
How long can I take linezolid?
Linezolid comes as a tablet and oral suspension (liquid) to take by mouth. It is usually taken with or without food twice a day (every 12 hours) for 10 to 28 days. Children 11 years of age and younger usually take linezolid with or without food two to three times a day (every 8 to 12 hours) for 10 to 28 days.
What is Xylox?
Uses. This medication is used to treat the symptoms of too much stomach acid such as stomach upset, heartburn, and acid indigestion. Aluminum and magnesium antacids work quickly to lower the acid in the stomach. Liquid antacids usually work faster/better than tablets or capsules.
What is another name for linezolid?
Zyvox (linezolid) is an antibacterial drug used to treat susceptible Gram-positive infections (for example, Staphylococcus and Streptococcus spp.). Zyvox is available in other countries under the generic name linezolid.
What kind of antibiotic is linezolid?
Who should not use linezolid?
You should not use linezolid if you are allergic to it. Do not use linezolid if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, methylene blue injection, phenelzine, rasagiline, selegiline, and tranylcypromine.
What is the generic name for Imuran?
Generic Name: azathioprine Azathioprine is used to prevent organ rejection in people who have received a kidney transplant. It is usually taken along with other medications to allow your new kidney to function normally. Azathioprine is also used to treat rheumatoid arthritis.
What kind of bacteria are oxazolidinones effective against?
Oxazolidinones are a new group of antibiotics. These synthetic drugs are active against a large spectrum of Gram-positive bacteria, including methicillin- and vancomycin-resistant staphylococci, vancomycin-resistant enterococci, penicillin-resistant pneumococci and anaerobes.
Where can I find a list of oxazolidinones?
Int J Antimicrob Agents. 2004 Feb;23 (2):113-9. doi: 10.1016/j.ijantimicag.2003.11.003. 1 Department of Pathology, Penn State University Hershey Medical Center, H083, 500 University Drive, PO Box 850 Hershey, PA 17033, USA. Oxazolidinones are a new group of antibiotics.
What are the bioavailability characteristics of oxazolidinones?
Tedizolid and linezolid are both oxazolidinones and share many characteristics such as activity against Gram-positive bacteria, the same mechanism of action and high oral bioavailability. Synthesis and biological activity of novel oxazolidinones, Bioorg Med Chem Letters.
How does oxazolidinones block the initiation complex?
Oxazolidinones block the initiation complex formation, by binding to the 50S ribosomal subunit, resulting in a bacteriostatic action2.  reported a range of antibiotic residues in foods: 20% sulfonamides, 19% fluoroquinolones, 15% aminoglycosides, 15% amphenicols, 15% beta-lactams, 8% oxazolidinones, and 8% tetracyclines.