Is poorly differentiated adenocarcinoma curable?

It is now clear that some patients with poorly differentiated carcinoma of unknown primary site have extremely responsive neoplasms, and some are curable with combination chemotherapy.

How long do you live after cancer spreads to liver?

In one small study of people with metastatic hepatocellular carcinoma, those whose liver cancer had spread to their lymph nodes or distant organs had an average survival rate of 4 and 11 months, depending on the severity of their liver damage and whether they received treatment.

What is adenocarcinoma in the liver?

Metastatic adenocarcinoma is the most common type of liver tumor by far. The most common sources of these metastases are primary lung, breast, and colorectal carcinomas. 1 As many as 60% of all metastatic adenocarcinomas are of unknown origin at the time of initial clinical presentation.

What is the life expectancy of someone with metastatic cancer?

A patient with widespread metastasis or with metastasis to the lymph nodes has a life expectancy of less than six weeks. A patient with metastasis to the brain has a more variable life expectancy (one to 16 months) depending on the number and location of lesions and the specifics of treatment.

What is the treatment for poorly differentiated adenocarcinoma?

Radiation therapy is usually offered after surgery for poorly differentiated carcinoma. It is used to kill any cancer cells and normal thyroid tissue that remain after surgery, treat cancer that has spread to lymph nodes or other parts of the body and control the growth of the cancer.

What is survival rate of poorly differentiated carcinoma?

The median survival time was 43 months. Sixteen patients survived for more than 10 years (maximum 297 months). The five- and 10-year cause specific survival rates for Stages I, II, III and IV disease were 100 and 100%, 80 and 27%, 83 and 83%, and 38 and 31%, respectively.

What happens in the final stages of liver cancer?

Symptoms of end-stage liver disease may include: Easy bleeding or bruising. Persistent or recurring yellowing of your skin and eyes (jaundice) Intense itching.

Can metastatic adenocarcinoma be cured?

In some situations, metastatic cancer can be cured, but most commonly, treatment does not cure the cancer. But doctors can treat it to slow its growth and reduce symptoms. It is possible to live for many months or years with certain types of cancer, even after the development of metastatic disease.

What does poorly differentiated mean?

poorly differentiated. Oncology adjective Referring to a malignancy in which the malignant cells bear minimal resemblance to the cell from which they arose.

What are poorly differentiated cells?

Poorly differentiated cells may be similar in appearance to the original cells from which they developed, but they may not be able to do all of the jobs expected of healthy immune cells. Cells that are poorly differentiated are less mature, more likely to grow fast, and also generally more susceptible to chemotherapy.

What is moderately differentiated adenocarcinoma?

Moderately differentiated adenocarcinoma is made up of cells that, for the most part, resemble normal, healthy cells. These cells have some malformations in their components and may divide at an increased rate but are not considered to be as aggressive as cells that are poorly differentiated.

How does liver cancer kill a person?

Liver cancer causes death in a few ways. Aside from distant spread to the brain or lung, causing bleeding, seizures, or other indirect causes of death like blood clots in the lung or heart, the cancer can block the bile ducts, causing jaundice , and eventually death, it can erode into the nearby intestines,…