How do you administer remifentanil?

Administering Remifentanil after an hypnotic agent will reduce the incidence of muscle rigidity. Remifentanil can be administered at an infusion rate of 0.5 to 1 microgram/kg/min, with or without an initial bolus injection of 1 microgram/kg given over not less than 30 seconds.

How do you dilute remifentanil for infusion?

For manually-controlled infusion Remifentanil can be diluted to concentrations of 20 to 250 micrograms/ml (50 micrograms/ml is the recommended dilution for adults and 20 to 25 micrograms/ml for paediatric patients aged 1 year and over). For TCI the recommended dilution of Remifentanil is 20 to 50 micrograms /ml.

What is the side effects of remifentanil?

More common

  • Blurred vision.
  • difficult or troubled breathing.
  • irregular, fast or slow, or shallow breathing.
  • lightheadedness, dizziness, or fainting.
  • muscle stiffness or tightness.
  • pale or blue lips, fingernails, or skin.
  • slow or irregular heartbeat.
  • unusual tiredness or weakness.

Does remifentanil cause bradycardia?

Remifentanil can cause bradycardia either by parasympathetic activation or by other negative chronotropic effects. The high frequency (HF) component of heart rate variability (HRV) is a marker of parasympathetic activity.

Can propofol cause bradycardia?

In controlled clinical trials, propofol significantly increased the risk of bradycardia compared with other anaesthetics (number-needed-to-harm 11.3 (95% confidence interval 7.7-21)).

Is diamorphine better than pethidine?

Injections – diamorphine This is an opioid injection with similar actions and side effects to pethidine, taking 30 minutes to work. Diamorphine has been shown to be a little better for pain relief in labour than pethidine and many women are more satisfied with diamorphine.

How is the infusion rate of remifentanil calculated?

The dose of remifentanil when used as an infusion is calculated in µ −1 .min −1. Certain infusion pumps can calculate the rate in ml.h −1 when the concentration of the drug and the dose required are entered. When you do not have one of these clever pumps, you need a calculator or one of the infusion rate tables supplied by Ultiva.

How much remifentanil should I take for pain?

Usual Adult Dose for Pain. INDUCTION of Anesthesia (through intubation): 0.5 to 1 mcg/kg/min via continuous IV infusion; an initial dose of 1 mcg/kg over 30 to 60 seconds may be administered. -If endotracheal intubation is to occur less than 8 minutes after start of the induction infusion, an initial IV dose should be given.

How often should I inject remifentanil with propofol?

-With Isoflurane at 0.4 to 1.5 MAC or Propofol at 100 to 200 mcg/kg/min: Continuous IV infusion at 0.25 mcg/kg/min (range 0.05 to 2 mcg/kg/min) -An IV bolus of 1 mcg/kg over 30 to 60 seconds may be used every 2 to 5 minutes as needed in response to light anesthesia or transient episodes of intense surgical stress.

How often should I give my Child remifentanil?

Usual Pediatric Dose for Anesthesia. Birth to 2 months old: -Continuous IV Infusion (with 70% nitrous oxide): 0.4 mcg/kg/min (range 0.4 to 1 mcg/kg/min) -Supplemental IV bolus of 1 mcg/kg every 2 to 5 minutes may be given in response to light anesthesia or transient episodes of intense surgical stress. 1 to 12 years: