How common is juvenile nasopharyngeal angiofibroma?

How common is nasopharyngeal angiofibroma? Nasopharyngeal angiofibroma is very rare. It accounts for 1/5000 to 1/50,000 head and neck tumors.

What is a juvenile angiofibroma?

Juvenile nasopharyngeal angiofibroma (JNA) is a benign vascular tumor that appears in the nasal cavity. Although it is non-malignant (not cancerous), it can expand quickly and extensively.

How do you diagnose Angiofibroma?

Tests for diagnosing angiofibroma An MRI or CT scan of the head and facial bones confirms the clinical diagnosis of angiofibroma and shows the extension of the tumor.

Why nasopharyngeal angiofibroma is common in adolescent males?

It most commonly affects adolescent males (because it is a hormone-sensitive tumor). Though it is a benign tumor, it is locally invasive and can invade the nose, cheek, orbit (frog face deformity), or brain.

Is juvenile nasopharyngeal angiofibroma?

Juvenile nasopharyngeal angiofibroma (JNA) is a rare benign tumor arising predominantly in the nasopharynx of adolescent males. It is an aggressive neoplasm and shows a propensity for destructive local spread often extending to the base of the skull and into the cranium.

How is Angiofibroma removed?

Angiofibromas can be safely & effectively removed by shave excision or electrosurgery, and less commonly using liquid nitrogen. Do not attempt self-removal of angiofibromas as that can often lead to permanent scars.

How is juvenile angiofibroma diagnosed?

How Is a Juvenile Nasopharyngeal Angiofibroma Diagnosed?

  1. MRI (magnetic resonance imaging)
  2. CT or CAT scan (computerized tomography)
  3. X-rays that show blood vessels in and around the tumor (angiography)
  4. sometimes, a biopsy (taking a sample of the growth for testing)

What is the cause of Angiofibroma?

What causes angiofibromas? Angiofibromas are caused by a local overgrowth of collagen, fibroblasts, and blood vessels. In tuberous sclerosis, mutations are present in tuberous sclerosis complex 1 (TSC1), which encodes the protein hamartin, and tuberous sclerosis complex 2 (TSC2) which encodes the protein tuberin.

Is Angiofibroma cancerous?

A benign (not cancer) tumor that is made up of blood vessels and fibrous (connective) tissue. Angiofibromas usually appear as small, red bumps on the face, especially on the nose and cheeks.

What causes Angiofibroma on face?

What is facial Angiofibroma?

Facial angiofibromas are hamartomatous growths that are closely associated with tuberous sclerosis complex and, in fact, they constitute one of the main diagnostic criteria for that disease. These lesions composed of blood vessels and fibrous tissue appear on the face at an early age.

Do fibrous papules go away on their own?

Fibrous papules do not usually cause any symptoms. They are removed either because of cosmetic reasons or because a histology test is required.

Can a female get nasopharyngeal angiofibroma ( na )?

‘Juvenile’ nasopharyngeal angiofibroma (NA) occurs almost exclusively in males, but has also been documented in females, albeit infrequently ( 1 – 5 ). When a diagnosis of NA is made in a female patient, caution is necessary to exclude the possibility of a conventional nasal or antrochoanal polyp with fibrosis.

Are there any female patients with angiofibroma?

Only rare cases of nasopharyngeal angiofibroma in female patients have been documented to date, and some authors believe that sex chromosome studies are indicated in such cases. The pathogenesis of nasopharyngeal angiofibroma remains unknown, but it has been hypothesized that it is a testosterone‑dependent tumor.

Why is it called juvenile angiofibroma ( JNA )?

The nasopharyngeal angiofibroma tumor is made mostly of blood vessels, which can result in frequent nosebleeds. The condition is also called juvenile nasopharyngeal angiofibroma (JNA) because the vast majority of these tumors grow in adolescent males. Doctors also call it juvenile angiofibroma (JA).

What are the complications associated with juvenile nasopharyngeal angiofibroma ( JNA )?

What are the complications associated with juvenile nasopharyngeal angiofibroma (JNA)? If left untreated, nasopharyngeal angiofibroma can lead to: Trouble breathing ; Vision, hearing and speech problems; Facial deformities such as droopy eyelids or bulging eyes; Loss of sense of smell; Severe nosebleeds and massive blood loss; Mental status change